Nature Made Vitamin B Complex
Vitamin B12, also called cobalamin, is a water-soluble nature made vitamin b complex essential for normal brain function (it is involved in the synthesis of neurotransmitters), nervous system (it is essential to maintaining the integrity of the nervous system and especially of the sheath myelin that protects nerves and enhances their operation) and blood formation. This is one of eight B vitamins It is normally involved as a cofactor in the metabolism of every cell in the human body, particularly in the DNA synthesis and its regulation and in the fatty acid synthesis and energy production. It exists in several forms belonging to the family of cobalamin: cyanocobalamin, hydroxocobalamin, methylcobalamin and adenosylcobalamin, the first two forms are stable. The cobalamins have a chemical structure close to the central atom but heme iron is replaced by a cobalt atom, hence the name. A nature made vitamin b complex B12 deficiency causes a form of anemia, one of whose characteristics is the presence of red blood cells significantly increased in size (macrocytosis). The total synthesis of this nature made vitamin b complex biomolecule, conducted in 1972 by Robert Burns Woodward, Albert Eschenmoser and their team, asked a number of years. The source of this nature made vitamin b complex research begins with the description of a fatal anemia, pernicious anemia, by various authors including Thomas Addison and Michael Anton pernicious in the nineteenth century. Around 1920, George Whipple, George Minot and William Murphy (Nobel Prize in 1934) showed that extracts of liver as food supplements were likely to correct certain anemias. The liver extracts contain the extrinsic factor, that is to say, the B12 itself. William Castle has shown that there is a critical intrinsic factor, and nonexistent in patients with pernicious anemia and an extrinsic factor from food (liver, meat). nature made vitamin b complex B12 was isolated in 1948 by Karl Folker of Merck and Lester Smith of Glaxo. The three-dimensional configuration was identified by Dorothy Hodgkin (Nobel Prize in Chemistry in 1964). In 2007, researchers from MIT and Harvard Medical School completed the study of the synthesis of nature made vitamin b complex B12 by microorganisms [2]. The human body does not synthesize vitamin B12. In nature, this synthesis is performed by bacteria, lower fungi and algae. Herbivores would be able to absorb nature made vitamin b complex B12 produced by bacteria in their stomachs. Carnivores obtain their consuming herbivores. For humans, the main sources are meat, fish, milk and eggs. Vitamin B12 is absorbed by food a multi-step process. In the acidic environment of the stomach, it is separated from the food substrate by the gastric pepsins. It then binds to salivary R protein which it is released into the duodenum as a result of pancreatic proteases. It can then be associated with intrinsic factor, a glycoprotein secreted by connecting the parietal cells of the stomach. The complex of vitamin B12 and intrinsic factor goes through the entire small intestine before being absorbed in this form in the distal ileum. The assimilation of nature made vitamin b complex B12 is impaired when one of the above mechanisms is lacking, such as when the stomach does not produce intrinsic factor. The action of nature made vitamin b complex B12 appears to rest on its intervention in the synthesis of free erythrocyte protoporphyrin and the conversion of folic acid folinic acid. Vitamin B12 is involved in the synthesis of thymidine (a substance important for the metabolism of nucleotides), which plays an important role in building the cell nucleus and therefore in cell replication. Vitamin B12 has a marked effect on growth. This action must be compared with the activity of nature made vitamin b complex vis-à-vis the amino acids blood levels fall after administration of the vitamin. Bacterial contamination: theory, nature made vitamin b complex B12 may be present in all plant foods unwashed, as a result of bacterial contamination due to residues of soil or compost from excrement, for example, once, when the hygienic conditions were reduced, it was certainly so. However, today it is almost impossible in countries where vegetables and wash hands is always needed and possible [3]. nature made vitamin b complex B12 is very little (or not) in the plant world: the comfrey and most of the edible seaweed such as' porphyry '(Porphyra umbilicalis) were deemed to occur, but these results are today' Today overturned. The current consensus in the scientific community is that these molecules are variants that are not assimilated by man of the vitamin. The scientific literature contains contradictory publications on the subject, even if today the consensus seems to emerge. Because of potentially serious disorders that may be caused by a nature made vitamin b complex B12 deficiency, it is important for vegans ensure a reliable, through supplementation. This can be direct (tablets or vials of nature made vitamin b complex B12 available in pharmacies) or indirect (breakfast cereals, fruit juices, soy milk fortified with B12 . . enough). Most associations recommend vegan vegans to ensure their nature made vitamin b complex B12 as well, including the Vegan Society, Vegan Association's oldest (founded in 1944 in the UK) [5]. B12 supplements and fortified foods consumed by vegetarians is almost always produced industrially from bacterial cultures. Note that nature made vitamin b complex B12 found in meat and animal products comes mainly from the B12 supplement added to food for livestock and is therefore of the same origin as the B12 taken by vegans [6]. World production of nature made vitamin b complex B12 in 2008 amounted to about 35 tons [7] and was provided by four companies: one French - Sanofi-Aventis - and three Chinese [8]. Production appears to be increasing rapidly. It is nature made vitamin b complex by bacterial fermentation, probably using genetically modified organisms [9]. The bulk of this production [10] is for farming, food additive and injections for the animals and the remainder used for food and medicine people. Research has shown that high values ??of B12 in the blood of elderly patients with advanced cancer were a significant predictor of mortality risk [11]. Pharmacist Impact cites a British study showing that "seniors who have good levels of nature made vitamin b complex B12 present less risk of the volume of their brain to decrease with age. "The scientists found after 5 years of follow-up that "the decline of brain volume was greater in volunteers who had low levels of nature made vitamin b complex B12," said the fortnightly which also states that according to the researchers' calculations, "the seniors who had low nature made vitamin b complex B12 were six times more likely to see their brain volume decrease. " Lack of nature made vitamin b complex B12 malabsorption or her may cause anemia and combined sclerosis of the spinal part of a neuro-anemic syndrome. ? P. Geissbühler, B. Mermillod and Rapin CH (2000), serum nature made vitamin b complex B12 Levels Eleveted associeted with CRP as a predictive factor of Mortality in palliative care cancer patients. A prospective study over five years, Journal of Pain and Symptom Management, Vol. 20, issue 2, pp. 93-103). Copyright: The text is available under Creative Commons attribution share alike, other conditions may apply. See Terms of Use for more details and credit graphics. If reuse of text on this page, see how to cite authors and include the license. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc. . , Charitable organization governed by Section 501 (c) (3) of the Tax Code of the United States. . . .
